THE CELL - ENGLISH

                                                     

THE CELL - ENGLISH

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THE  CELL

       Cells are the structural and functional units of all living organisms. Cells were discovered by Robert hooke in 1665. Some organisms, such as bacteria, are unicellular, consisting of a single cell. Other organisms, such as humans, are multicellular, indicating that humans are made up of many cells

       Cells are the smallest independent units of life with different parts  that perform their own function  For the cells to survive some fundamental chemical activities occur within the cell. Each cell is an amazing unit of life; it can take in nutrients, convert these nutrients into energy, carry out specialised functions and reproduce as necessary.

       Human cells consists of-

       Cell membrane                                 Cytoplasm

       Nucleus                                                                                Mitochondria    

       Ribosome                                                            Endoplasmic reticulum

       Golgi body                                                          Lysosome

       Peroxisome                                                        Vacuole

CELL MEMBRANE-

       The cell membrane is a thin membrane that forms the outermost layer of a cell, and it is also called the plasma membrane. This membrane ensures the boundary and integrity of the cell and that its contents are separated from the surrounding environment. The cell membrane contains a variety of biological molecules, mainly proteins and lipids

       The cell membrane is made up of a double layer (bilayer) of phospholipid (fatty) molecules with  protein molecules interspersed between them.

       The phospholipid bilayer consists of a polar ‘head’ end, which is hydrophilic (water loving), and fatty acid ‘tails’, which are hydrophobic (water hating). The hydrophilic heads are situated on the outer and inner surfaces of the cell, while the hydrophobic areas point into the cell membrane

 

FUCNTIONS OF CELL MEMBRANE-

 

Ø  A Physical Barrier- The cell membrane surrounds all cells and physically separates the cytoplasm, which is the material that makes up the cell, from the extracellular fluid outside the cell. This protects all the components of the cell from the outside environment and allows separate activities to occur inside and outside the cell.

Ø  Selective Permeability- cell membranes are selectively permeable (or semi-permeable), meaning that only certain molecules can pass through them. Water, oxygen, and carbon dioxide can easily travel through the membrane. Generally, ions (e.g. sodium, potassium) and polar molecules cannot pass through the membrane.

Ø  Endocytosis and Exocytosis – Endocytosis is when a cell ingests relatively larger contents than the single ions or molecules that pass through channels. Through endocytosis, a cell can take in large quantities of molecules or even whole bacteria from the extracellular fluid. Exocytosis is when the cell releases these materials. 

Ø  Cell Signaling - Another important function of the membrane is to facilitate communication and signaling between cells. It does so through the use of various proteins and carbohydrates in the membrane. Proteins on the cell “mark” that cell so that other cells can identify it. 

 

CYTOPLASM –

       Cytoplasm refers to the thick solution that fills the cell, which includes the cytosol along with filaments, proteins, ions and macromolecular structures as well as the organelles suspended in the cytosol. The cytoplasm includes all of the material inside the cell and outside of the nucleus.

 

NUCLEUS-

       The cell nucleus is a large organelle of the cell which protects the majority of the genetic material (DNA) within each cell. The nucleus also produces the necessary precursors for protein synthesis. The DNA is used to form chromatin/chromosomes. The human cell contains 23 pairs of chromosomes. chromosomes are thread-like structures made up of strands of DNA and the histone proteins.

       A cell nucleus and nucleoplasm is surrounded by a double membrane, known as the nuclear membrane. This membrane covers and protects the chromosomes from physical and chemical damage. In a stained nucleus, a dark spot can be seen. This spot is the nucleolus. Within the nucleolus, the several different parts of ribosomes are produced and exported.

 

MITOCHONDRIA-

       Mitochondria (singular: mitochondrion) are organelles within  cells that produce adenosine triphosphate (ATP), the main energy molecule used by the cell. For this reason, the mitochondrion is sometimes referred to as “the powerhouse of the cell”. 

       Mitochondria have two membranes, an outer membrane and an inner membrane. The outer membrane covers the surface of the mitochondrion, while the inner membrane is located within and has many folds called cristae

       The amount of mitochondria in a cell depends on how much energy that cell needs to produce. Muscle cells, for example, have many mitochondria because they need to produce energy to move the body. Red blood cells, which carry oxygen to other cells, have none; they do not need to produce energy.

 

RIBOSOME-

       The ribosome is a highly complex cellular organelle. It is largely made up of specialized RNA known as ribosomal RNA (rRNA) and proteins. The ribosomal proteins and rRNAs are arranged into two distinct ribosomal pieces of different size, known generally as the large and small subunit of the ribosome. Ribosomes consist of two subunits that fit together 

       Ribosomes function to synthesize proteins. Proteins are needed for many cellular functions such as repairing damage or directing chemical processes. Ribosomes can be found floating within the cytoplasm or attached to the endoplasmic reticulum. Basically, their main function is to convert genetic code into an amino acid sequence and to build protein polymers from amino acid monomers.

 

ENDOPLASMIC RETICULUM-

       The endoplasmic reticulum (ER) is a large organelle made of membranous sheets and tubules that begin near the nucleus and extend across the cell. The endoplasmic reticulum creates, packages, and secretes many of the products created by a cell.

       There are two major types of ER within each cell – smooth endoplasmic reticulum (SER) and rough endoplasmic reticulum (RER). Each has distinct functions, and often, differing morphology. The SER is involved in lipid metabolism and acts as the calcium store for the cell. the RER is commonly seen close to the nucleus. It contains membrane-bound ribosomes that give it the characteristic ‘rough’ appearance. RER is involved in creating proteins. 

 

GOLGY BODY-

       The Golgi apparatus is an organelle in eukaryotic organisms that moves molecules from the endoplasmic reticulum to their destination. The organelle also modifies products of the endoplasmic reticulum to their final form. The Golgi apparatus is comprised of a series of flattened sacs that extend from the endoplasmic reticulum.

       The main function of the Golgi apparatus is the ability to deliver vesicles, or packets of various cell products, to different locations throughout the cell.

 

LYSOSOME-

       Lysosomes are specialized vesicles within cells that digest large molecules by the use of hydrolytic enzymes. Vesicles are small spheres of fluid surrounded by a lipid bilayer membrane, and they have roles in transporting molecules within the cell. A human cell contains around 300 of them. Not only do they digest large molecules, they are also responsible for breaking down and getting rid of waste products of the cell.

       They can also perform autophagy, which is the destruction of improperly functioning organelles. In addition, lysosomes have a role in phagocytosis, in white blood cells.

 

PEROXISOMES-

       Peroxisomes are organelles that can vary in shape, size and number depending on the energy needs of the cell. Peroxisomes are membrane-bound organelles in most eukaryotic cells, primarily involved in lipid metabolism and the conversion of reactive oxygen  such as hydrogen peroxide into safer molecules like water and oxygen.

       Their role in detoxifying and oxidizing a number of molecules, metabolic byproducts and drugs makes them a prominent part of kidney and liver cells.

 

VACULE-

       A vacuole is an organelle in cells which functions to hold various solutions or materials. This includes solutions that have been created and are being stored or excreted, and those that have been phagocytized, or engulfed, by the cell. A vacuole is simply a chamber surrounded by a membrane, which keeps the cytosol from being exposed to the contents inside.


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