CHOLERA IN ENGLISH
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CHOLERA-
Cholera is an acute
bacterial enteric disease characterized by sudden onset, profuse painless
watery stools (rice-water stool), nausea and profuse vomiting early in the
course of illness. In untreated cases, rapid dehydration, acidosis, circulatory
collapse, hypoglycaemia in children, and renal failure can rapidly lead to
death.
CAUSATIVE AGENT-
Cholera is caused
by a bacteria known as Vibrio cholerae. Only Vibrio cholerae serogroups
O1 and O139 are associated with the epidemiological characteristics and
clinical picture of cholera.
HOW IT SPREADS-
Cholera is acquired
through ingestion of an infective dose of contaminated food or water and can be
transmitted through many mechanisms. Contamination of drinking water occurs
usually at source, during transportation or during storage at home. Food may
also be contaminated by soiled hands during preparation or while eating.
Contaminated
surface waters, and unsafe domestic water storage methods results in extensive
waterborne transmission of cholera. Beverages prepared with contaminated water
and sold by street vendors, ice and even commercial bottled water have been
identified as vehicles in cholera transmission. Incubation period ranges from a
few hours to 5 days, usually 2-3 days.
CLINICAL MENIFESTATIONS-
Ø Sign and symptoms of cholera includes-
Ø profuse painless watery stools (rice-water stool -pale
milky appearance of stool),
Ø Nausea and profuse vomiting early in the course of
illness.
Ø Pain abdomen
Ø Lethargy.
Ø Signs of dehydration such as dry mouth, sunken eyes, loss
of skin turgor, irritability and fatigue.
Ø Muscular cramps.
Ø Low blood pressure,
Ø circulatory collapse and shock.
Ø Hypoglycemia and renal failure can rapidly lead to death.
DIAGNOSTIC INVESTIGATIONS-
Ø History and physical examination .
Ø Stool microscopic examination
Ø Stool culture after takingrectal swab and sending tolab
for culture
TREATMENT-
Ø Treatment with antibiotics is effective against cholera.
drugs of choice are doxicycline, tetracycline, TMP-SMX and erythromycin.
Ø Adequate hydration with
ORS or IV fluids as needed
PREVENTION-
Ø Early detection and prompt treatment of cases is the best
strategy to prevent further spread of cholera.
Ø Isolation: Hospitalization with enteric precautions is
desirable for severely ill patients.
Ø All soiled clothes and linen should be soaked in a
solution of 2 per cent chlorine and steam-sterilized.
Ø Use best possible cleanliness in food preparation and
handling. Pay particular attention to the storage of salads and other foods
served cold. These provisions apply to home and public eating places.
Ø Avoid eating uncovered food or water from market.
Ø Use best possible
milk hygiene practices such as pasteurization and refrigeration of milk.
Ø Health education regarding the importance of handwashing.
Suitable handwashing facilities, particularly for food handlers and attendants
involved in the care of patients and children, should be provided.
Ø Environmental
sanitation abolishing breeding places of flies is also a good measure to
prevent spread of cholera.
Ø Health education regarding the importance of safe
drinking water to prevent cholera should be given to general public. Methods of
water purification should be understood to all.
Ø Immunization with
cholera vaccine is a good method of prevention of cholera specially in endemic
areas.
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