TYPES OF ABORTION part 2 IN ENGLISH

                                                      

                                  TYPES OF ABORTION part 2 IN ENGLISH

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Types of Abortions PART 2

Missed abortion-

When the fetus is dead and retained inside the uterus for a variable period, it is called missed miscarriage. The causes of prolonged retention of the dead fetus in the uterus are not clear. Beyond 12 weeks, the retained fetus becomes macerated or mummified. The liquor amnii gets absorbed and the placenta becomes pale, thin and may be adherent.

Clinical manifestations-

The patient usually presents with features of threatened miscarriage followed by:

(1) Persistence of brownish vaginal discharge.

(2) Disappearance of pregnancy symptoms

(3)Retrogression of breast changes.

(4) Cessation of uterine growth which in fact becomes smaller in size.

(5) Non-audibility of the fetal heart sound even with Doppler ultrasound if it had been audible before.

(6) On PV examination cervix feels firm

(7) Immunological test for pregnancy becomes negative.

Management-

If pregnancy is less than 12 weeks: (i)  Medical

Management includes insertion of Prostaglandin E1 (misoprostol) 800 mg vaginally in the posterior fornix and repeated after 24 hours if needed. Expulsion usually occurs within 48 hours.

(ii) Suction evacuation or dilatation and evacuation is done either as a definitive treatment or it can be done when the medical method fails

If pregnancy is more than 12 weeks:

(a) Prostaglandin E1 analog (misoprostol) 200 μg tablet is inserted into the posterior vaginal fornix every 4 hours for a maximum of 5 times.

(b) Oxytocin—10–20 units of oxytocin in 500 mL of normal saline at 30 drops/min is started. If fails, escalating dose of oxytocin to the maximum of 200 mlU/min may be used with monitoring.

(c) Many patients need surgical evacuation following medical treatment after ultrasonography. 

(d) Dilatation and evacuation is done once the cervix becomes soft with use of PGE1. Otherwise cervical canal is dilated using the mechanical dilators or by laminaria tent. eacuation of the uterine cavity is done thereafter slowly.

Septic Abotion-

Any abortion associated with clinical evidences of infection of the uterus and its contents is called septic abortion. It is considered septic abortion  when there are: (1) rise of temperature of at least 100.4°F (38°C) for 24 hours or more, (2) offensive orpurulent vaginal discharge and (3) other evidences of pelvic infection such as lower abdominal pain and tenderness.

               Causes and Risk factors-

Main factor causing septic abortion is unsafe abortion technique by unqualified and unauthorized person. While the majority of cases, the infection occurs following illegal induced abortion but infection can occur even after spontaneous abortion.  by the sepsis are usually those normally present in the vagina (endogenous). The microorganisms are:-

(a)    Anaerobic—Bacteroides group (fragilis), anaerobic Streptococci, Clostridium welchii and tetanus bacillus.

(b)     AerobicEscherichia coli (E. coli), Klebsiella, Staphylococcus, Pseudomonas and group A beta-hemolytic Streptococcus (usually exogenous), methicillin-resistant Staphylococcus aureus

Clinical manifestations-

Depending upon the severity the clinical picture varies widely. These includes-

        „„The woman looks sick and anxious

        „„Temperature: >38°C

        „„Chills and rigors (suggest-bacteremia)

        „„Persistent tachycardia ≥ 90 bpm (spreading infection)

        „„Hypothermia (if in shock) < 36°C

        „„Abdominal or chest pain

        Tachypnea (RR) > 20/min

        „„Impaired mental state

        „„Diarrhea and/or vomiting

        „„Renal angle tenderness

Diagnostic Investigations-

(1) Cervical or high vaginal swab is taken prior to internal examination for—

(a)    culture in aerobic and anaerobic media to find out the dominant microorganisms,

(b)     sensitivity of the microorganisms to antibiotics and

(c)     smear for Gram stain.

 (2) Blood for hemoglobin estimation, total and differential count of white cells, ABO and Rh grouping.

(3) Urine analysis including culture.

(4) Ultrasonography of pelvis and abdomen to detect intrauterine retained products of conception

(5) Blood culture

(6) Serum electrolytes

Cinical Grading-

Septic abortions are of three types as per severity-

Grade I: The infection is localized in the uterus.

Grade II: The infection spreads beyond the uterus to the parametrium, tubes and ovaries or pelvic  peritoneum.

Grade III: Generalized peritonitis and/or endotoxic shock or jaundice or acute renal failure.

Management-

In case of Grade I:

(1)Broad spectrum Antibiotics  to control infection.

(2) Prophylactic anti gas gangrene serum of 8,000 units and 3,000 units of anti tetanus serum

intramuscularly are given if there is a history of unsafe abortion.

(3) Analgesics and sedatives as per need.

 (4)Blood transfusion is given to improve anemia and body resistance.

(5)Evacuation of the uterus: As abortion is often incomplete, evacuation should be performed at a convenient time within 24 hours following antibiotic therapy.

In case of Grade II:

(1)Broad spectrum Antibiotics  to control infection. Empirical therapy is started first and is changed when culture sensitivity report is available including Piperacillin-tazobactam and carbapenems:.

(2) Prophylactic anti gas gangrene serum of 8,000 units and 3,000 units of anti tetanus serum intramuscularly are given if there is a history of unsafe abortion.

 (3) Analgesics and sedatives as per need.

(4)Blood transfusion is given to improve anemia and body resistance.

(5) Evacuation of the uterus—Evacuation should be withheld for at least 48 hours when the infection is controlled and is localized, the only exception being excessive bleeding.

In case of Grade III:

(1) Clinical monitoring: To note pulse, respiration, temperature, urinary output and progress of the pain, tenderness and mass in lower abdomen.

(2) Broad spectrum Antibiotics  to control infection. Empirical therapy is started first and is changed when culture sensitivity report is available including Piperacillin-tazobactam and carbapenems.

(3) Prophylactic anti gas gangrene serum of 8,000 units and 3,000 units of anti tetanus serum intramuscularly are given if there is a history of unsafe abortion.

(4) Supportive therapy is directed to treat generalized peritonitis by gastric suction and intravenous crystalloids infusion. Management of endotoxic shock or renal failure.

(5)Patient may need intensive care unit management in case of respiratory, cardiovascular and kidney problems appear.

(6) Laprotomy with Removal of the uterus should be done irrespective of parity. Adnexa is to be removed or preserved according to the pathology found. Thorough inspection of the gut and omentum for evidence of any injury is mandatory

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